Investigate into conolidine has led to discovery of an opioid receptor in the human body named ACKR3/CXCR7. ACKR3 seems to be one of the most desired target for conolidine, which also disregards the opposite four classical opioid receptors(three). Given the mechanism of motion of conolidine as opposed to opioids https://messiahrlbbq.tribunablog.com/not-known-details-about-conoldine-alternative-natural-pain-relief-51893590