Butabarbital will decrease the level or outcome of fedratinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Influence of coadministering a robust CYP3A4 inducer with fedratinib has not been analyzed. butabarbital will reduce the level or result of carvedilol by impacting hepatic enzyme CYP2C9/ten metabolism. https://wayneq246prt0.celticwiki.com/user