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DNA ligases seal five′-PO4 and 3′-OH polynucleotide ends through 3 nucleotidyl transfer actions involving ligase-adenylate and DNA-adenylate intermediates. DNA ligases are essential guardians of genomic integrity, and ligase dysfunction underlies human genetic disorder syndromes. Crystal structures of DNA ligases certain to nucleotide and nucleic acid substrates have illuminated how https://www-ligaz-bet-online-spor82582.like-blogs.com/27902671/fascination-about-official-ufabet

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