In older people, That is essential to know as polypharmacy is prevalent and may potentiate the risk of DDIs and ADRs. Therefore, concurrent ingestion of CYP2D6 inhibitors or inducers could potentiate or block tramadol conversion into ODT and This may maximize or lower efficacy/ADRs in the prescribed tramadol. Literature https://jolenew838kap2.blogaritma.com/profile